Advecta Plus Flea Protection for Cats

Advecta® Plus Flea Protection for Cats contains the same active ingredients as Advantage® II for Cats*. This fast-acting, long-lasting formula starts killing on contact, no biting required, within 12 hours of application while actively preventing flea reinfestations for up to 30 days breaking the flea lifecycle.

*Advecta Plus® is not manufactured by or distributed by Bayer. Advantage® II is a registered trademark of Bayer Healthcare, LLC.

Breaks the flea life cycle
Advecta flea treatment and prevention for dogs and cats is effective at eliminating and controlling pests in your house and on your pets. While we certainly believe that Advecta offers the best bang for your buck when it comes to dog and cat flea treatment, we can be a little biased. That’s why we invite you to read what our customer are saying about Advecta. Not only are they happy, in many cases Advecta has exceeded their flea elimination expectations. Read below!


Do not allow children to apply product. To prevent harm to you and your cat, read the entire label and package insert before each use. Follow all directions and precautionary statements carefully. Use on cats only. Do not use on dogs or other animals.

Directions for Use: It is a violation of Federal Law to use this product in a manner inconsistent with its labeling. Read Entire Label.

Before Each Use Restrictions: Use only on cats or on kittens 8 weeks of age or older weighing more than 5 lbs. Do not use on other animals. Do not exceed labeled dosage amounts for cats. Do not apply more than one (1) tube per treatment. Do not have contact or allow children to have contacted with treated area until completely dry.

How to Apply for Cats:

  1. Remove one applicator tube from the package.  
  2. Hold applicator tube in an upright position facing away from you and your pet’s face and eyes. Pull cap off tube. 
  3. Turn the cap around and place other end of cap back on tube. 
  4. Twist cap to break seal, then remove cap from tube. 
  5. The cat should be standing for easy application. Part the hair on the cat’s back, between the shoulder blades, until the skin is visible. Place the tip of the tube on the skin and squeeze the tube to expel the entire contents directly on the skin. 
  6. Discard empty tube as described in the Storage and Disposal section. 
  7. Under normal conditions the product is effective for a month. However, in case of severe flea infestation, retreatment may be necessary earlier than four weeks. Do not re-treat more often than once every seven (7) days. After flea control is obtained, return to a monthly retreatment schedule.


Hazards to Humans: WARNING. Causes substantial but temporary eye injury.  Harmful if swallowed.  Do not get in eyes or on clothing.  Wash hands thoroughly with soap and water after handling and before eating, drinking, chewing gum, using tobacco or using the toilet. 

Hazards to Domestic Animals: FOR EXTERNAL USE ON CATS ONLY. Individual sensitivities, while rare, may occur after using ANY pesticide product for cats. Do not treat your cat with more than one pesticide product at a time.  Over-dosing your cat can result in serious illness and even death. Consult a veterinarian before using this product on medicated, debilitated, aged, pregnant or nursing cats.


Q. What are the benefits of using this product? 

A. This specially formulated fast acting flea squeeze on topical treatment starts working on contact in 12 hours, no biting required, kills all flea life stages (adults, eggs, and larvae), is easy to use and waterproof.

Q. How long will it take for this product to begin to work? 

A. The product should begin to kill fleas within 24-48 hours but may take up to 72 hours to reach its full effectiveness. 

Q. Does this product kill ticks? 

A. No, this product does not kill ticks.

Q. What is the difference between this product and oral flea products? 

A. This product is applied to your pet topically and kills fleas through contact with the product on your pet’s skin, so fleas don’t have to bite to die.  With oral flea medications, fleas must bite your furry family member and be exposed to the medication in the pet before the fleas are killed. 

Q. How do these products spread over a pet’s body?  How long does this take? 

A. This product is topical only and is dispersed over your furry family member’s body by the natural oils on their skin and attaches to the hair follicle. This process can take up to 24 hours. 

Q. How does this product work?

A. This product contains two active ingredients: imidacloprid that attacks the flea’s nervous system, paralyzing and ultimately killing them and pyriproxyfen, an insect growth regulator (IGR) that prevents flea eggs and larvae from maturing into adults. This combination plays a crucial role in existing infestations because you might only be aware of adult fleas which represent around 5% of a full infestation plus immature flea life stages (flea eggs, larvae and pupae) that exist in your environment make up the rest of the infestation are almost invisible to the naked eye.